深入探讨造血干细胞移植治疗多发性硬化症的潜力

Deep dive into the potential of Hematopoietic Stem Cell Transplant in treating Multiple SclerosisAmanda L. Piquet, MDAssociate Professor of NeurologyDirector, Autoimmune Neurology ProgramNeuroimmunology, Neuroinfectious Disease and Neurohospitalist SectionsUniversity of Colorado School of MedicineObjectives•Describe hematopoietic stem cell transplant – what is it?•Background and history of transplant in MS•Current data in stem cell transplant for MS – where are we now?•Future research – where are we going?What is hematopoietic stem cell transplant?What it is NOT?•Medical Tourism (especially in foreign countries)•“Infusion” of stem cells into spinal fluid or through and IV through “stem cell clinics”Swart JF, Delemarre EM, van Wijk F, Boelens JJ, Kuball J, van Laar JM, Wulffraat NM. Haematopoietic stem cell transplantation for autoimmune diseases. Nat Rev Rheumatol. 2017. Hematopoietic stem cell transplant (HSCT) involves administering healthy hematopoietic stem cells (either self or do