安进JPM2025Presentation_Final

ROBERT A. BRADWAY, CHAIRMAN AND CHIEF EXECUTIVE OFFICERJanuary 13, 202543rdANNUAL J.P. MORGAN HEALTHCARE CONFERENCE2Provided January 13, 2025, as part of an oral presentation and is qualified by such, contains forward-looking statements, actualresults may vary materially; Amgen disclaims any duty to update.SAFE HARBOR STATEMENTThispresentationcontainsforward-lookingstatementsthatarebasedonthecurrentexpectationsandbeliefsofAmgen.Allstatements,otherthanstatementsofhistoricalfact,arestatementsthatcouldbedeemedforward-lookingstatements,includinganystatementsontheoutcome,benefitsandsynergiesofcollaborations,orpotentialcollaborations,withanyothercompany(includingBeiGene,Ltd.orKyowaKirinCo.,Ltd.),theperformanceofOtezla®(apremilast)(includinganticipatedOtezlasalesgrowthandthetimingofnon-GAAPEPSaccretion),ouracquisitionsofTeneobio,Inc.,ChemoCentryx,Inc.,orHorizonTherapeuticsplc(includingtheprospectiveperformanceandoutlookofHorizon’sbusiness,performanceandopportunities,anypotentialstrategicbenef