用于新兴污染物降解的酶纳米杂化物

Enzyme Nanohybrids for Emerging Contaminant DegradationYifanGao, Meng Wang, KshitijaShah, Shaily MahendraUCLA Civil and Environmental EngineeringAcknowledgments▪UCLA Faculty: ▪Leonard Rome, Bruce Dunn, EricHoek, Patrick Allard, ChongLiu, JunyoungPark, Valerie Kickhoefer▪UCLA Students and postdocs: ▪Benjamin Croze, Yichang Chen, Esther Lan, DavidZgonc, MinhaoXiao,HaiyuanZou,Glenn Nurwono, Yu Chen, Randy Chen, JingyuWang, YongchaoXie▪USEPA: ▪Quinn Birch, MallikarjunaNadagouda▪University of Georgia: ▪QingguoHuangMicrobial Enzymes BiotransformContaminants3Created by BioRender.comNarayanan etal.,JEM, 2023Enzyme Immobilization4Surface BindingCrosslinkingEntrapment++++++-------GlassPolymersActivated CarbonNanoparticlesImmobilizationEnzymesimmobilizedinto/ontonanomaterials for stability and longevityYifanGaoetal.,Biotech.Adv.,2022Nanoscale: Size Matters•Nanoscale = 1-100 nm in at least 1 dimension •Increased surface area = increase reactivity•Wave/Particle duality = unique nanoscalepropertiesK